Gene Expression Literature Summary

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Nrp1  neuropilin 1   (Synonyms: Neuropilin-1, NP-1, Npn1, NPN-1)
Results	Reference
1*	J:121340 Anderson RB, Bergner AJ, Taniguchi M, Fujisawa H, Forrai A, Robb L, Young HM, Effects of different regions of the developing gut on the migration of enteric neural crest-derived cells: a role for Sema3A, but not Sema3F. Dev Biol. 2007 May 1;305(1):287-99
1	J:175836 Cariboni A, Davidson K, Dozio E, Memi F, Schwarz Q, Stossi F, Parnavelas JG, Ruhrberg C, VEGF signalling controls GnRH neuron survival via NRP1 independently of KDR and blood vessels. Development. 2011 Sep;138(17):3723-33
1	J:169003 Cool J, DeFalco TJ, Capel B, Vascular-mesenchymal cross-talk through Vegf and Pdgf drives organ patterning. Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):167-72
1	J:211622 DeFalco T, Bhattacharya I, Williams AV, Sams DM, Capel B, Yolk-sac-derived macrophages regulate fetal testis vascularization and morphogenesis. Proc Natl Acad Sci U S A. 2014 Jun 10;111(23):E2384-93
1	J:174966 Erskine L, Reijntjes S, Pratt T, Denti L, Schwarz Q, Vieira JM, Alakakone B, Shewan D, Ruhrberg C, VEGF signaling through neuropilin 1 guides commissural axon crossing at the optic chiasm. Neuron. 2011 Jun 9;70(5):951-65
1	J:147285 Eshkar-Oren I, Viukov SV, Salameh S, Krief S, Oh CD, Akiyama H, Gerber HP, Ferrara N, Zelzer E, The forming limb skeleton serves as a signaling center for limb vasculature patterning via regulation of Vegf. Development. 2009 Apr;136(8):1263-72
1	J:218050 Gelfand MV, Hagan N, Tata A, Oh WJ, Lacoste B, Kang KT, Kopycinska J, Bischoff J, Wang JH, Gu C, Neuropilin-1 functions as a VEGFR2 co-receptor to guide developmental angiogenesis independent of ligand binding. Elife. 2014;3:e03720
1	J:304874 Hatanaka Y, Matsumoto T, Yanagawa Y, Fujisawa H, Murakami F, Masu M, Distinct roles of neuropilin 1 signaling for radial and tangential extension of callosal axons. J Comp Neurol. 2009 May 20;514(3):215-25
1	J:94593 Inaki K, Nishimura S, Nakashiba T, Itohara S, Yoshihara Y, Laminar organization of the developing lateral olfactory tract revealed by differential expression of cell recognition molecules. J Comp Neurol. 2004 Nov 15;479(3):243-56
1*	J:65419 Ito T, Kagoshima M, Sasaki Y, Li C, Udaka N, Kitsukawa T, Fujisawa H, Taniguchi M, Yagi T, Kitamura H, Goshima Y, Repulsive axon guidance molecule Sema3A inhibits branching morphogenesis of fetal mouse lung. Mech Dev. 2000 Oct;97(1-2):35-45
1	J:320186 Kalisch-Smith JI, Morris EC, Strevens MAA, Redpath AN, Klaourakis K, Szumska D, Outhwaite JE, Sun X, Vieira JM, Smart N, De Val S, Riley PR, Sparrow DB, Analysis of Placental Arteriovenous Formation Reveals New Insights Into Embryos With Congenital Heart Defects. Front Genet. 2021;12:806136
1*	J:30682 Kawakami A, Kitsukawa T, Takagi S, Fujisawa H, Developmentally regulated expression of a cell surface protein, neuropilin, in the mouse nervous system. J Neurobiol. 1996 Jan;29(1):1-17
1	J:84337 Kawano H, Horie M, Honma S, Kawamura K, Takeuchi K, Kimura S, Aberrant trajectory of ascending dopaminergic pathway in mice lacking Nkx2.1. Exp Neurol. 2003 Jul;182(1):103-12
1*	J:95356 Kettunen P, Loes S, Furmanek T, Fjeld K, Kvinnsland IH, Behar O, Yagi T, Fujisawa H, Vainio S, Taniguchi M, Luukko K, Coordination of trigeminal axon navigation and patterning with tooth organ formation: epithelial-mesenchymal interactions, and epithelial Wnt4 and Tgf{beta}1 regulate semaphorin 3a expression in the dental mesenchyme. Development. 2005 Jan;132(2):323-334
1*	J:30346 Kitsukawa T, Shimono A, Kawakami A, Kondoh H, Fujisawa H, Overexpression of a membrane protein, neuropilin, in chimeric mice causes anomalies in the cardiovascular system, nervous system and limbs. Development. 1995 Dec;121(12):4309-18
1*	J:167053 Ko JA, Mizuno Y, Yanai R, Chikama T, Sonoda KH, Expression of semaphorin 3A and its receptors during mouse corneal development. Biochem Biophys Res Commun. 2010 Dec 17;403(3-4):305-9
1	J:166127 Kuhnert F, Mancuso MR, Shamloo A, Wang HT, Choksi V, Florek M, Su H, Fruttiger M, Young WL, Heilshorn SC, Kuo CJ, Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124. Science. 2010 Nov 12;330(6006):985-9
1	J:317364 Li SY, Gu X, Heinrich A, Hurley EG, Capel B, DeFalco T, Loss of Mafb and Maf distorts myeloid cell ratios and disrupts fetal mouse testis vascularization and organogenesis. Biol Reprod. 2021 Oct 11;105(4):958-975
1*	J:56403 Makinen T, Olofsson B, Karpanen T, Hellman U, Soker S, Klagsbrun M, Eriksson U, Alitalo K, Differential binding of vascular endothelial growth factor B splice and proteolytic isoforms to neuropilin-1. J Biol Chem. 1999 Jul 23;274(30):21217-22
1	J:242704 Marcos S, Monnier C, Rovira X, Fouveaut C, Pitteloud N, Ango F, Dode C, Hardelin JP, Defective signaling through plexin-A1 compromises the development of the peripheral olfactory system and neuroendocrine reproductive axis in mice. Hum Mol Genet. 2017 Jun 01;26(11):2006-2017
1	J:164033 Miller AM, Maurer LR, Zou DJ, Firestein S, Greer CA, Axon fasciculation in the developing olfactory nerve. Neural Dev. 2010;5(1):20
1	J:249972 Munro DAD, Hohenstein P, Coate TM, Davies JA, Refuting the hypothesis that semaphorin-3f/neuropilin-2 exclude blood vessels from the cap mesenchyme in the developing kidney. Dev Dyn. 2017 Dec;246(12):1047-1056
1*	J:117851 Pan Q, Chanthery Y, Liang WC, Stawicki S, Mak J, Rathore N, Tong RK, Kowalski J, Yee SF, Pacheco G, Ross S, Cheng Z, Le Couter J, Plowman G, Peale F, Koch AW, Wu Y, Bagri A, Tessier-Lavigne M, Watts RJ, Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth. Cancer Cell. 2007 Jan;11(1):53-67
1	J:225355 Plein A, Calmont A, Fantin A, Denti L, Anderson NA, Scambler PJ, Ruhrberg C, Neural crest-derived SEMA3C activates endothelial NRP1 for cardiac outflow tract septation. J Clin Invest. 2015 Jul 1;125(7):2661-76
1*	J:65135 Schwarting GA, Kostek C, Ahmad N, Dibble C, Pays L, Puschel AW, Semaphorin 3A is required for guidance of olfactory axons in mice. J Neurosci. 2000 Oct 15;20(20):7691-7
1	J:184006 Tang K, Rubenstein JL, Tsai SY, Tsai MJ, COUP-TFII controls amygdala patterning by regulating neuropilin expression. Development. 2012 May;139(9):1630-9
1	J:221661 Wiszniak S, Mackenzie FE, Anderson P, Kabbara S, Ruhrberg C, Schwarz Q, Neural crest cell-derived VEGF promotes embryonic jaw extension. Proc Natl Acad Sci U S A. 2015 May 12;112(19):6086-91